Despite substantial progress in confronting the global HIV-1 epidemic since its inception in the 1980s, better approaches for both treatment and prevention will be necessary to end the epidemic and remain a top public health priority.Antiretroviral therapy (ART) has been effective in extending lives, but at a cost of lifelong adherence to treatment
History-dependent excitability as a single-cell substrate of transient memory for information discrimination.
Neurons react differently to incoming stimuli depending upon their previous history of stimulation.This property can be considered Bath Book as a single-cell substrate for transient memory, or context-dependent information processing: depending upon the current context that the neuron "sees" through the subset of the network impinging on it in the
Soaring Energy Prices: Understanding Public Engagement on Twitter Using Sentiment Analysis and Topic Modeling With Transformers
Energy prices have gone up gradually since last year, but a drastic hike has been observed recently in the past couple of months, affecting people’s thrift.This, coupled with the load shedding and energy shortages in some parts of the world, led many to show anger and bitterness on the streets and on social media.Despite subsidies offered by
Phospholipid, arachidonate and eicosanoid signaling in schizophrenia
This paper reviews the potential role of arachidonic acid in the pathophysiology of schizophrenia.We discuss how abnormal levels of arachidonic acid may arise, and how dysregulation of signaling molecules derived from it have the potential 50 Ohm RG58 to disrupt not only dopamine signaling, but numerous other physiological processes associated with